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Amicus Therapeutics Wants Effective Treatment Options for Rare, Orphan Diseases

Amicus Therapeutics, a well-known biotechnology company, based in New Jersey, wanted to develop effective treatment options for rare, orphan diseases. The firm is in the pipeline of developing treatment solutions for multiple human genetic disorders. Its migalastat, is a drug that is in the final stage of development would help the physicians to treat people who are struggling with Fabry disease, based on their genetic diagnosis. Amicus Therapeutics confirmed that migalastat is moving to commercial launch stage. SD-101 is another medication that is also in the late-stage of development which would be the first-to-market therapy to address Epidermolysis Bullosa, an unusual genetic connective tissue disorder. Learn more about job offerings of Amicus Therapeutics at Indeed.

SD-101 is in the phase three stage of the testing, and it is also expected to be made commercially available anytime soon. Amicus Therapeutics is also designing a biologics program named ATB200/AT2221. It is a specifically designed Pompe disease ERT allowing it to use along with any pharmacological chaperone. The biotechnology firm is also known for using its Chaperone-Advanced Replacement Therapy platform and biologics to develop new enzyme replacement therapies or ERTs for various diseases including Lysosomal Storage Disorders or LSDs, Pompe disease, Farby disease, and more. Apart from these advanced staged programs, Amicus Therapeutics is also developing many other solutions to address other orphan diseases as well.


The biotechnology company was established in the year 2002, and it went for a public listing in 2007. Initially, the company was funded by a number of venture capitalist firms including, Canaan Partners, New Enterprise Associates, and Radius Ventures. Amicus Therapeutics has received multiple grants in the past including The Michael J. Fox Foundation grant that amounts to $500,000 in 2010. Alzheimer’s Drug Discovery Foundation also offered a grant of $210,300 in 2010 to work together with Icahn School of Medicine for supporting pre-clinical works. Amicus Therapeutics also completed some acquisitions recently to expand their expertise in biotechnology and genetics research. Learn more about the company at

Dr. Edward Honig- New York City Cardiologist with a Heart of Gold

Dr. Edward Honig, MD is a New York City certified cardiologist who specializes in the care of the cardiovascular system. Cardiologist helps in finding, preventing and also treating diseases of blood vessels and heart. Dr. Edward further clarifies that the cardiovascular system includes all the vital parts of your body that are arteries, blood vessels, and heart.

Most people do not visit cardiologists like Dr. Edward unless sent by their primary care physicians. Unfortunately, once the patient is sent to a cardiologist it’s usually something serious has happened. He advises that there are situations a person should visit a cardiologist. Some of the situations include when a person has high cholesterol, a family history with cardiologist’s system problem, high blood pressure if a person is a smoker or have ever smoked and in case you have diabetes. Dr. Edward Honig states that seeing a cardiologist earlier is one way of preventing an existing vital problem and getting a way forward to healthy life.

Whether you see cardiologists in the hospital or private clinic, the cardiologists will perform physical examinations and review your medical history. Dr. Honig of New York states that some of the examinations include checking lungs, weight, blood vessels, blood pressure, weight, and heart. Some problems are easily diagnosed by the symptoms and doctor’s exam. Additional tests a physician include a blood test, x-ray, and ECG. Since each patient has a unique case, the cardiologist might recommend a change of lifestyle.

According to Dr. Edward of Glen Cove Hospital in NYC, you should see cardiologists if you have chest pains, shortness of breath, or dizzy spells or if your general doctor feels you have a heart-related condition. The cardiologist might perform ECG evaluation or heart murmurs to determine the main problem. If you have a heart problem, the doctor will counsel and guide you on how to treat the disease. Importantly cardiologists are directly involved in the treatment of heart failure, heart attacks, and severe heart disturbances, and rhythm says, Honig.

The ECG is done using the echocardiograms that send sound wave pictures of your heart to see its function. Dr. Hogin further explains that abnormal heartbeats are easily detected using the Ambulatory ECG that keeps track of the heart activities, and the Cardiac Catheter is sometimes used to take your heart pictures.

Dr. Edward Honig, MD works at Glen Cove, New York city as a senior cardiologist; he has his office located in a secure access location that makes it easy to seek help. As a cardiologist in a big hospital, Honig has a verified experience in this field. As a cardiologist, Dr, Honig has undergone extensive education that includes attending four years of medical school and three more years in general internal medicine. To specialize as a cardiologist, Dr. Edward went through three more years of specialized training. That means Dr. Edward Hogan has spent more than a decade training in education and clinical preparations. Additionally, he has also passed American Board of Internal Medicine rigorous two day’s exam to become certified.