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Cameron Clokie is a renowned Oral and Maxillofacial Surgeon, and also works as a professor of Oral and Maxillofacial Surgery at the University of Toronto. His interest in bone regeneration has seen him publish numerous papers and deliver presentations at national and international platforms on bone reconstruction and restoration. Mr. Clokie is also the CEO of Induce Biologics Inc. and received his Doctor of Dental Surgery (DDS) in 1985 and a doctorate in bone regeneration at the McGill University in 1992.
Regenerative medicine has gained popularity with blood transfusion, bone marrow transplants and cell therapy on burn victims taking the lead. However, scientists are yet to produce mainstream solutions for the treatment of chronic conditions. Majority of the clinical projects lack efficacy and are expensive, hence the high costs of treatment. Mr. Clokie’s experience has seen him spread his knowledge to students, and now to patients after the establishment of Induce Biologics Inc. The technology involves the use of a protein that stimulates the change of adult stem cells into bone.
Through Induce Technologies, Cameron Clokie hopes to reduce the costs of bone regeneration through more research. While he has successfully enabled jawbone regeneration for a few patients, more research into the production of BMP is still ongoing. Bone Morphogenetic Protein (BMP) was discovered in the 1950’s by Marshall Urist, and Mr. Clokie had the opportunity to study under him. The protein has the power to affect stem cells, even in adults and enable the growth of various human tissue types. Currently, Clokie is working towards the production of larger quantities on BMP through goat’s milk, instead of acquiring it from other sources. He believes that the step could significantly reduce the costs of bone regeneration and make it affordable for more people.
Induce Technologies Inc. is currently using URIST™, the lead product that contains a carrier and BMP. The carrier provides a continuous multi-phase delivery of BMP, thus allowing lower dosages of BMP to the body. Lower dosages lower the costs of the treatment and also overcome the toxicity and adverse effects associated with high dosages of BMP. Hopefully, Cameron Clokie’s efforts will yield cost-effective solutions for bone regeneration, and also pave the way for further research in the future.
Osteoarthritis is the most common form of arthritis. It is also known as degenerative joint disease. This is when the cartilage located between two joints is degenerated or worn away.
So why is the degeneration of cartilage a problem? Once the cartilage between the bones has been worn away, it causes the two bones that used be connected and cushioned with cartilage to rub against each other. This is what creates the pain that is typical of people who are suffering from arthritis. As we age, our joints can also become weaker and the pain more severe and chronic as a result. Watch this video on Youtube.
If one is suffering from osteoarthritis, there are some simple things one can do to lessen the pain. Stretching and getting up constantly if working in a sedentary position such as in an office chair can help. Quitting smoking, losing weight and avoid repetitive motions on the job and at home can also decrease the symptoms of arthritis. Avoiding heavy or strenuous exercise is a good idea as well.
Exercise can actually be a good way to reduce pain and manage osteoarthritis. Choose low impact exercises such as swimming, stretching and walking. Exercise that strengthens joints is also good for anybody suffering from arthritis. Exercise that strains the joints such as running and repetitive motion activities in sports such as tennis swings can aggravate the condition and should limited.
There is also a wide range of medical options that can treat osteoarthritis. This includes, physical therapy, medication and topical gels. When all other options have been exhausted, somebody suffering from osteoarthritis should consider surgery. Visit crunchbase.com to know more about Osteo Relief Institute.
The Osteo Relief Institute is a medical institution that is staffed by orthopedic surgeons who can perform surgery for osteoarthritis relief. Procedures performed at the Osteo Relief Institute can help people who are suffering arthritis in the knees, lower joint swelling, spinal pain, grinding knees and osteoarthritis of the knee. The procedures done at the Osteo Relief Institute are FDA cleared and are performed only be skilled experts in the field of orthopedics.
If you are considering surgery for your arthritis, you can request a free information kit from the Osteo Relief Institute that can help you decide if surgery is the best option for you. The Osteo Relief Institute is based in New Jersey, but has locations across the United States. It uses state of the art technology and FDA approved procedures.
Amicus Therapeutics, a well-known biotechnology company, based in New Jersey, wanted to develop effective treatment options for rare, orphan diseases. The firm is in the pipeline of developing treatment solutions for multiple human genetic disorders. Its migalastat, is a drug that is in the final stage of development would help the physicians to treat people who are struggling with Fabry disease, based on their genetic diagnosis. Amicus Therapeutics confirmed that migalastat is moving to commercial launch stage. SD-101 is another medication that is also in the late-stage of development which would be the first-to-market therapy to address Epidermolysis Bullosa, an unusual genetic connective tissue disorder. Learn more about job offerings of Amicus Therapeutics at Indeed.
SD-101 is in the phase three stage of the testing, and it is also expected to be made commercially available anytime soon. Amicus Therapeutics is also designing a biologics program named ATB200/AT2221. It is a specifically designed Pompe disease ERT allowing it to use along with any pharmacological chaperone. The biotechnology firm is also known for using its Chaperone-Advanced Replacement Therapy platform and biologics to develop new enzyme replacement therapies or ERTs for various diseases including Lysosomal Storage Disorders or LSDs, Pompe disease, Farby disease, and more. Apart from these advanced staged programs, Amicus Therapeutics is also developing many other solutions to address other orphan diseases as well.
The biotechnology company was established in the year 2002, and it went for a public listing in 2007. Initially, the company was funded by a number of venture capitalist firms including, Canaan Partners, New Enterprise Associates, and Radius Ventures. Amicus Therapeutics has received multiple grants in the past including The Michael J. Fox Foundation grant that amounts to $500,000 in 2010. Alzheimer’s Drug Discovery Foundation also offered a grant of $210,300 in 2010 to work together with Icahn School of Medicine for supporting pre-clinical works. Amicus Therapeutics also completed some acquisitions recently to expand their expertise in biotechnology and genetics research. Learn more about the company at crunchbase.com.
Dr. Edward Honig, MD is a New York City certified cardiologist who specializes in the care of the cardiovascular system. Cardiologist helps in finding, preventing and also treating diseases of blood vessels and heart. Dr. Edward further clarifies that the cardiovascular system includes all the vital parts of your body that are arteries, blood vessels, and heart.
Most people do not visit cardiologists like Dr. Edward unless sent by their primary care physicians. Unfortunately, once the patient is sent to a cardiologist it’s usually something serious has happened. He advises that there are situations a person should visit a cardiologist. Some of the situations include when a person has high cholesterol, a family history with cardiologist’s system problem, high blood pressure if a person is a smoker or have ever smoked and in case you have diabetes. Dr. Edward Honig states that seeing a cardiologist earlier is one way of preventing an existing vital problem and getting a way forward to healthy life.
Whether you see cardiologists in the hospital or private clinic, the cardiologists will perform physical examinations and review your medical history. Dr. Honig of New York states that some of the examinations include checking lungs, weight, blood vessels, blood pressure, weight, and heart. Some problems are easily diagnosed by the symptoms and doctor’s exam. Additional tests a physician include a blood test, x-ray, and ECG. Since each patient has a unique case, the cardiologist might recommend a change of lifestyle.
According to Dr. Edward of Glen Cove Hospital in NYC, you should see cardiologists if you have chest pains, shortness of breath, or dizzy spells or if your general doctor feels you have a heart-related condition. The cardiologist might perform ECG evaluation or heart murmurs to determine the main problem. If you have a heart problem, the doctor will counsel and guide you on how to treat the disease. Importantly cardiologists are directly involved in the treatment of heart failure, heart attacks, and severe heart disturbances, and rhythm says, Honig.
The ECG is done using the echocardiograms that send sound wave pictures of your heart to see its function. Dr. Hogin further explains that abnormal heartbeats are easily detected using the Ambulatory ECG that keeps track of the heart activities, and the Cardiac Catheter is sometimes used to take your heart pictures.
Dr. Edward Honig, MD works at Glen Cove, New York city as a senior cardiologist; he has his office located in a secure access location that makes it easy to seek help. As a cardiologist in a big hospital, Honig has a verified experience in this field. As a cardiologist, Dr, Honig has undergone extensive education that includes attending four years of medical school and three more years in general internal medicine. To specialize as a cardiologist, Dr. Edward went through three more years of specialized training. That means Dr. Edward Hogan has spent more than a decade training in education and clinical preparations. Additionally, he has also passed American Board of Internal Medicine rigorous two day’s exam to become certified.